- Nicholas "Nick" Cassidy as The Cat in the Hat
- Lydia Mercer as Daisy-Head Mayzie
- Joey Cassidy as Horton the Elephant
- Michael "Mike" Ackerman as Thing One
- Angela 'Angie' Maria Lopez as Cindy Lou Who
- David "Dave" Englander as Thing Two
- Suzie Morales as Sarah-Hall Small
- Jackie "Jack" Dougherty as Joey
- Dante Marcus as Sam-I-Am
- Nestor as Yertle the Turtle
- Franklin "Frank" Cassidy and Valet as The Grinch
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