- John Hatcher as Peter Griffin
- Screwface as Stewie Griffin
- Max as Chris Griffin
- Charles as Cleveland Brown
- Leslie as Lois Griffin
- Melissa Hatcher as Meg Griffin
- Tracey Hatcher as Dr. Amanda Rebecca
- Tito Barco as Mort Goldman
- Duvall as Jesus
- Nesta as Mayor Adam West
- Money as Joe Swanson
- Hector as Neil Goldman
- Nago as Seamus
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