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Contents 1 Patient Information 2 Treatment 3 MDS Treatment 4 Time Line

[edit] Patient Information

Age: 12

Sex: Male

Diagnosed: 10/03

Location: Connecticut

Diagnosis: DSRCT

Current: As of August 2006 no evidence of DSRCT

Hospital: Connecticut Children's Medical Center

Oncologists:

Primary Pediatric Oncologist: Eileen Gillan, MD

Pediatric Oncology Surgeon: . Michael P. La Quaglia, FACS, FRCS

Consultant: Brian Kushner, MD

Secondary Issue: Myelodysplastic Syndrome (MDS), a form of pre-leukemia diagnosed March 28,2006

Caringbridge Journal

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[edit] Treatment

Chemotherapy: P6 protocol

Cytoxan (Cyclophosphamide); Adriamycin (Doxorubicin); Vincristine

Cycles with Topotecan and Cytoxan (Cyclophosphamide);

Surgery: 100% tumor removal. All cancer dead except one tumor which had small microscopic live cells.

Radiation: 30 radiation treatments. 20 over the entire abdomen and pelvic region and then an additional 10 over the area where the only tumor that still had living microscopic cancer cells was located

Chemotherapy: 6 months of oral VP-16 (etoposide)

Stem Cell Rescue - Four hours and done

[edit] MDS Treatment

Myelodysplastic Syndromes

Chemotherapy

Allogenic Stem Cell Transplant - Receives stem cells from brother

[edit] Time Line

Date	Test	Treatment	Chemicals	Result
10/8/03	0	Chemotherapy Cycle 1	P6 protocol	Abdominal tumors
11/03	0	Chemotherapy Cycle 2	P6	0
12/03	CT	Chemotherapy Cycle 3	P6	Tumors shrinking
1/12/04	0	Chemotherapy Cycle 4	P6	0
2/25/04	None	Surgery	0	Was able to remove all visible tumors. Pathology reported all cancer cells dead except for small microscopic area on one.
3/10/04	0	Chemotherapy Cycle 5	P6	0
4/5/04	0	Chemotherapy Cycle 6	P6	0
4/24/04	CT/PET	0	0	No evidence of disease
5/14/04	0	Radiation	0	Start 30 radiation treatments. 20 over the entire abdomen and pelvic region and then an additional 10 over the area where the only tumor that still had living microscopic cancer cells was located
6/17/04	0	Chemotherapy & Radiation	0	Final chemo and radiation sessions
7/1/04	0	Stem Cell Rescue	0	Completed in four hours
8/7/04	CT/PET	Chemotherapy	Oral dose VP-16	No evidence of disease
9/16/04	0	Day surgery to remove Hickman line	Oral Chemo -VP-16	0
10/04	0	0	Chemotheapy -VP-16	Oral Chemo
11/04	0	Chemotherapy VP-16	Oral Chemo	0
12/1/04	CT/PET	Chemotherapy - VP-16	5th round of oral chemo	No evidence of disease
1/26/05	0	Chemotherapy - VP-16	6th round of oral chemo	0
2/23/05	CT/PET	0	0	No evidence of disease
3/05	0	0	0	0
4/05	0	0	0	0
5/27/05	CT/PET	0	0	No evidence of disease
6/05	0	0	0	0
7/05	0	0	0	0
8/25/05	CT/PET	0	0	No evidence of disease
9/05	0	0	0	0
10/05	0	0	0	0
11/05	0	0	0	0
12/20/05	CT/PET	0	0	No evidence of disease
1/06	0	0	0	0
2/06	0	0	0	0
3/31/06	Blood plateletts low for unknown reason. Bone marrow aspiration procedure done.	0	0	Diagnosed with a pre-leukemia syndrome called MDS (side effect caused by chemo treatment). Treatment same as if leukemia.
4/6/06	CT	0	0	No evidence of DSRCT
4/18/06	0	Chemotherapy	0	To treat the MDS
4/30/06	0	Chemotherapy	0	To treat the MDS
5/12/06	0	Chemotherapy	Cytarabine and Aspariginase	Unexplained leg pains.
6/23/06	0	(Allogeneic) Stem Cell Transplant	0	Received stem cells from brother
7/29/06	0	0	0	Release from hospital month after Stem Cell transplant
8/06	PET	0	0	No evidence of DSRCT
9/06	0	0	0	0
10/06	0	0	0	100 days since BMT for MDS and doing well
11/06	0	0	0	0
12/06	0	0	0	0
1/07	0	0	0	0
2/07	0	0	0	0
3/07	0	0	0	0
4/07	0	0	0	0
5/07	0	0	0	0
6/07	CT/PET	0	0	No evidence of disease
7/07	0	0	0	0
8/07	0	0	0	0
9/07	0	0	0	0
10/07	0	0	0	0
11/07	0	0	0	0
12/07	0	0	0	0
1/08	0	0	0	0
2/08	0	0	0	0
3/08	0	0	0	0
4/08	0	0	0	0

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