• Megamind as Fry
  • Roxanne as Leela
  • Gru (from Despicable Me) as Bender
  • Lady Scott as Amy
  • Lord Scott as Hermes
  • Dr.Nefario (from Despicable Me) as Professor Farnsworth
  • Minion as Zoidberg
  • Metro Man as Zapp Brannigan

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