- Stuart as Hiro Hamada
- Tom as Baymax
- Kevin the Minion as Tadashi
- Tim as Wasabi-No-Ginger
- Jorge as GoGo Tomago
- Gru as Fred
- Herb as Robert Callaghan
- Margo (from Despicable Me) as Cass
- Mr. O'Hare (from Dr. Seuss' The Lorax) as Alister Krei
- T-Rex as Yokai
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