- Moe (from The Simpsons) as The Lorax
- Horton (from Horton Hears a Who) as Once-ler
- Homer (from The Simpsons) as Young Once-ler
- Mr. Peabody as Ted
- Jewel (from Rio) as Audrey
- Sherman as Pipsqueak
- Paul Peterson as Mr. O'Hare
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