• Kermit the Frog as Papa Smurf
  • Miss Piggy as Smurfette
  • Dr. Bunsen Honeydew as Brainy Smurf
  • Beaker as Clumsy Smurf
  • Sam the Eagle as Grouchy Smurf
  • Gonzo the Great as Gutsy Smurf
  • Johnny Fiama as Vanity Smurf
  • Ernst Stravos Grouper as Gargamel
  • Toralei Stripe (from Monster High) as Vexy
  • Robot Lincoln as Hackus
  • David Hoggselhoff as Patrick Winslow
  • Spamela Hamderson as Grace Winslow

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