My Little Avengers is a crossover between My Little Pony and The Avengers.
- Ashleigh Ball as Rainbow Dash/Rainbow Thor and Applejack/Captain Equestria
- Claire Corlett as Sweetie Belle/Sweetie Machine
- Michelle Creber as Apple Bloom
- Andrea Libman as Pinkie Pie/Pinkeye and Fluttershy
- Nicole Oliver as Princess Celestia, the All-Mother
- Madeline Peters as Scootaloo/Thundaloo
- Tabitha St. Germain as Rarity/Iron Mare and Princess Luna, the All-Seeing
- Tara Strong as Twilight Sparkle/Twilight Widow
- Cathy Weseluck as Spike the Dragon
- Lou Ferrigno as Flutterhulk
- While Fluttershy is usually voiced by Andrea Libman, the Flutterhulk's growling, roaring, grunting and other vocal effects are provided by Lou Ferrigno.
- It is related to Fluttershy is that in one episode, due to a Poison Joke plant, she got a man's voice. This masculine-voiced version of her is known commonly as Flutterguy.