My Little Pony/Ren and Stimpy

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Spike as Ren (Both are small, plus Spike was a dog in Equestria Girls)

Derpy as Stimpy(They're both idiots)

Dinky as Stinky(Their names rhyme and Stinky is Stimpy's son and Dinky is Derpy's daughter)

Big Macintosh as Mr. Horse

Rainbow Dash as Powdered Toast Man(They're both heroes)

Lightning Dust as Waffle Woman(They're both enemies to the heroes)

Pinkie Pie as Sven

Twilight Sparkle as Ren's Mom

Shining Armor as Ren's Dad

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