• Stan Marsh as Indiana Jones
  • Oakie Doke as Henry Jones Sr.
  • Numbuh 2 as Mutt Williams
  • Wendy Testaburger as Marion Ravenwood
  • Wuya as Elsa Schneider
  • Tessie Bear as Willie Scott
  • Noddy as Short Round
  • Brock as Sallah
  • Shelly Marsh as Irina Spalko
  • Eric Cartman as Rene Belloq
  • Sly The Goblin as Colonel Dietrich
  • Gobbo The Goblin as Arnold Toht
  • Jack Spicer as Lao Che
  • Dr. K as Colonel Vogel
  • Harley as Walter Donovan
  • Mr. Burns as Mola Ram
  • Homer Simpson as George Mac MacHale
  • Budgie as Harold Ox Oxley
  • Numbuh 1 as Marcus Brody

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