- Sheriff Ed Tom Bell as Gonzo the Great
- Anton Chigurh as Uncle Deadly
- Llewelyn Moss as Kermit the Frog
- Carla Jean Moss as Miss Piggy
- Carson Wells as Dr. Teeth
- Deputy Wendell as Floyd Pepper
- Loretta Bell as Janice
- Ellis as Sam the Eagle
- Agnes Kracik as Miss Mousey
- Man who hires Wells as Jim Henson
- Thomas Thayer as Beauregard
- Boy on Bike as Rizzo the Rat
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