- Kako as Ed
- Ned Flanders (from The Simpsons) as Edd
- Oobi as Eddy
- Maestru as Kevin
- Sandy (from SpongeBob SquarePants) as Nazz
- Larry the Lobster (from SpongeBob SquarePants) as Rolf
- Grampu as Johnny
- Uma as Sarah
- Angus as Jimmy
- Dr. Doofenshmirtz (from Phineas and Ferb) as Eddy's Brother
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