- Calvin Jarrett as Homer Simpson
- Beth Jarrett as Marge Simpson
- Condrad Jarrett as Bart Simpson
- Dr. Tyrone C. Berger as Mayor Joe Quimby
- Jeannine Pratt as Allison Taylor
- Coach Salan as Principal Seymour Skinner
- Karen Aldrich as Lisa Simpson
- Joe Lazenby as Dr. Julius Hibbert
- Ray Hanley as Kent Brockman
- Sloan as Officer Lou
- Ward as Waylon Smithers, Jr.
- Audrey as Maude Flanders
- Kevin Stillman as Mr. Burns
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