- Peggy Sue Bodell as Lois Griffin
- Charlie Bodell as Peter Griffin
- Richard Norvik as Brian Griffin
- Carol Heath as Meg Griffin
- Maddy Nagle as Susie Swanson
- Michael Fitzsimmons as Cleveland Brown
- Walter Getz as Chris Griffin
- Delores Dodge as Jillian
- Rosalie Testa as Dr. Amanda Rebecca
- Arthur Nagle as Dr. Hartman
- Jack Kelcher as Jesus
- Terry as Joe Swanson
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