Version 1

  • Ash as Carlos 
  • Misty as Ms. Frizzle
  • Brock as Tim 
  • Drew as Ralphie 
  • Nurse Joy as Keesha 
  • Max as Arnold 
  • Dawn as Wanda
  • May as Phoebe 
  • Iris as Dorothy Ann
  • Ritchie as Mikey
  • Pikachu as The Magic School Bus
  • Jigglypuff as Liz
  • Serena as Janet 

Version 2

  • Clefairy as Ms. Frizzle
  • Oshawott as Ralphie
  • Latios as Carlos
  • Skitty as Wanda
  • Buneary as Dorothy Ann
  • Latias as Keesha
  • Charizard as Arnold
  • Squirtle as Tim
  • Jigglypuff as Phoebe
  • Pikachu as The Magic School Bus
  • Togepi as Liz
  • Mew as Janet

Version 3 (Made by Pikachufreak)

  • Wilhelmina as Ms. Frizzle
  • Temacu as Liz
  • Ephraim as The Magic School Bus
  • Ash as Ralphie
  • Brock as Tim 
  • Danny as Carlos
  • Nelson as Arnold 
  • Bailey as Keesha
  • Marina as Dorothy Ann
  • Krystal as Phoebe 
  • Sakura as Wanda 
  • Ephraim as Mikey
  • Chigusa as Janet

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