- Ramona Quimby as Janice
- Beezus Quimby as Miss Piggy
- Henry Huggins as Kermit the Frog
- Aunt Bea as Annie Sue Pig
- Robert Quimby as Jim Henson
- Hobart as Gonzo the Great
- Howie Kemp as Rizzo the Rat
- Mrs. Meacham as Camilla the Chicken
- Roberta Quimby as Miss Mousey
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