- Ramona Quimby as Ellie Mae
- Beezus Quimby as Miss Bianca
- Henry Huggins as Bernard
- Robert Quimby as The Chairman
- Dorothy Quimby as Penny
- Hobart as Cody
- Howie Kemp as Gramps
- Mrs. Meacham as Joanna the Goanna
- Susan Kushner as Madame Medusa
- and more
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