• Jack T. Colton as Ash Ketchum
  • Joan Wilder as Misty
  • Ralph as Brock
  • Ira as May
  • Juan as Pikachu
  • Colonel Zolo as Mewtwo
  • Gloria as Zoey
  • Elaine Wilder as Iris
  • Mrs. Irwin as Nurse Joy
  • Super as Drew
  • Santos as Gary Oak
  • Hefty Woman as Francesca Ketchum
  • Bus Driver as Professor Birch
  • Bad Hombre as Buizel
  • Hotel Clerk as Tracey
  • Angelina as Buneary
  • Jesse Gerrard as Cilan
  • Grogan as Harley

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