- Tommy Pickles as Lilo
- Phil DeVille as Stitch
- Lil DeVille as Fibber
- Betty DeVille as Nani
- Howard DeVille as David
- Homer Simpson (from The Simpsons) as Cobra
- N Gin (from Crash Bandicoot) as Pleakley
- Dr. Neo Cortex (from Crash Bandicoot) as Jumba
- Reptar as Gantu
- Angelica Pickles as Sparky
- Dil Pickles as Reuben
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