San Franciscowas one of the five cities that held a large amount of the USA's population is located.
Although founded as a Spanish colony in the 18th century, San Francisco first gained prominence in 1849 after gold was discovered in California. Thousands of American fortune seekers, known as the 49ers, settled in the city.
By 1893, San Francisco had a growing and diverse population, including professional gamblers like Frederick La Rouque and Joe Falling Hawk, as well as aspiring writers such as Jack London. The city also attracted a number of alien visitors, unbeknown to the Human population. Among these included the malevolent Devidians, and the El-Aurian Guinan, who masqueraded as a wealthy local patron.
During the Refuge Era, the city is one of the most populated cities in the United States.