Schaut
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[edit] In Memory
Nikki
[edit] Patient Information
Age: 12
Sex: Female
Diagnosed: 4/03
Location: Minnesota
Diagnosis: DSRCT
Hospital Children's Hospitals and Clinics of Minnesota
- Oncologist
Relapse: 5/16/05 Tumor found between lungs.
Remission: No evidence of disease as of July 2006
Relapse: 9/23/07 diagnosed with Leukemia
Passed away: 11/23/07
[edit] Treatment
First Line Chemotherapy
- Cycle 1 - Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
- Cycle 2 - Etoposide, Ifosfamide, with Mesna
- Gleevac given daily.
Radiation - 20+ sessions
Surgery #1 - Removed all visible tumors from pelvic area, underside of the liver, and top of the liver. Reports that 99% of the cancer cells were dead.
Chemotherapy
- Etoposide and Ifosfamide
- Gleevac given daily
Low Dose Maintenace Chemotherapy
- 1st Treatment: 100mg VP 16 (Etoposide) 21 days on and 7 off
- 2nd Treatment: 50mg VP 16 (Etoposide) 21 days on 7 off
Surgery #2 - Removed tumor that was a bit on the heart and in a nerve area.
Radiation - 4 -6 weeks after relapse
Chemotherapy - treatment for Leukemia
[edit] Time Line
| Date | Test | Treatment | Chemicals | Result |
|---|---|---|---|---|
| 4/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | Tumors in pelvic area, underside of the liver, and top of the liver. |
| 5/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 5/18/03 | 0 | 0 | 0 | Admitted to PICU with inflammation of brain |
| 5/23/03 | CT, MRI, spinal tap, EEG | 0 | 0 | Tumors shrinking considerably |
| 6/15/03 | 0 | Harvest stem cells | 0 | 0 |
| 6/23/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 7/14/03 | CT | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | Tumors continue to shrink |
| 8/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 9/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 9/15/03 | CT | 0 | 0 | Tumors still shrinking. One tumor has shrunk 3cm and is now 7cm. Watching three suspicious areas. |
| 9/23/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 10/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 11/19/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 11/24/03 | 0 | 0 | 0 | Fanconi Kidney caused by chemo. Has a leaky kidney. Needs to have phosphorus and magnesium, calcium and potassium levels monitored. |
| 12/15/03 | 0 | Chemotherapy | Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna | 0 |
| 1/10/04 | CT | 0 | 0 | Some tumors have gotten 1-2cm smaller. Area of concern is the liver area which showed 1 /2 inches by 2, which is larger than before. Few other suspicious mass areas, not conclusive for cancer. |
| 1/22/04 | 0 | Chemotherapy | Etoposide and Ifosfamide | 0 |
| 2/14/04 | CT | 0 | 0 | Stable, set for surgery |
| 2/18/04 | 0 | Surgery | 0 | Removed all visible tumors from pelvic area, underside of the liver, and top of the liver. Reports that 99% of the cancer cells were dead. |
| 3/04 | 0 | Chemotherapy | Etoposide and Ifosfamide, Gleevac | 0 |
| 3/31/04 | CT | Radiation 20+ days | 0 | Noted a suspicious mass |
| 4/14/04 | PET | 0 | 0 | Mass was negative for cancer |
| 5/3//04 | 0 | Daily Gleevac | 0 | Finished radiation |
| 5/26/04 | CT | 0 | 0 | No change. Possible cysts around kidneys that have always been there. |
| 6/04 | 0 | Chemotherapy | Etoposide and Ifosfamide | 0 |
| 7/14/04 | CT | Chemotherapy | Etoposide and Ifosfamide, Gleevac | No visible signs, and even a small spot near liver has disappeared. |
| 7/26/04 | 0 | Chemotherapy | Etoposide and Ifosfamide, Gleevac | 0 |
| 8/04 | 0 | 0 | Gleevac | 0 |
| 9/3/04 | 0 | Chemotherapy | Etoposide and Ifosfamide, Gleevac | 0 |
| 9/23/04 | CT | Low dose Maintenance chemotherapy | Gleevac daily | Clear. Still no tumors. Still see small area they believe are cysts. |
| 10/04 | 0 | 0 | Gleevac | 0 |
| 11/5/04 | CT | 0 | 0 | Still clear. |
| 12/23/04 | CT | 0 | 0 | Clear |
| 1/25/05 | CT | 0 | 0 | Clear, no evidence of disease. |
| 2/05 | 0 | Day surgery | 0 | Removed central line |
| 3/14/05 | CT | 0 | 0 | Clear |
| 4/05 | 0 | 0 | Gleevac | 0 |
| 5/16/05 | CT/PET | 0 | Gleevac | Spot appeared between the lungs. |
| 5/21/05 | 0 | Biopsy | 0 | Relapse: Tumor between lungs |
| 6/19/05 | 0 | Surgery - four hours | 0 | Tumor was a bit on the heart and in a nerve area |
| 7/25/05 | CT | 0 | 0 | Baseline. Abdomen looks good. Still areas around lungs. |
| 8/3/05 | 0 | Radiation - next 4-6 weeks. Low dose Maintenance chemotherapy | Stopped taking Gleevac. Started taking 100ml VP16/Etoposide daily. | 0 |
| 8/15/05 | PET | Radiation. Low dose Maintenance chemotherapy | 100mg Etoposide (VP-16) 21 days on 7 off | Just area being radiated may or may not be tumor. Other spots are not tumor related. |
| 9/05 | 0 | 0 | 0 | Break from VP16/Etoposide |
| 10/3/05 | 0 | Low dose Maintenance chemotherapy | 100mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 10/7/05 | CT | 0 | 0 | Clear |
| 11/05 | 0 | 0 | 0 | Sample of tumor sent to Stehlin Foundation for Research |
| 11/28/05 | CT | 0 | 0 | Clear |
| 12/05 | 0 | 0 | 0 | 0 |
| 1/24/06 | CT | 0 | 0 | No evidence of disease |
| 2/06 | 0 | 0 | 0 | 0 |
| 3/06 | 0 | 0 | 0 | Off Etoposide |
| 4/06 | 0 | 0 | 0 | 0 |
| 5/06 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 6/13/06 | CT | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | No evidence of disease |
| 7/28/06 | CT | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | No evidence of disease |
| 8/06 | 0 | Low dose maintence chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 9/06 | CT | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | No evidence of disease |
| 10/06 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 11/06 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 12/06 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 1/15/07 | CT | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | No evidence of disease. |
| 2/07 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 3/07 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 4/07 | 0 | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | 0 |
| 5/15/07 | CT | Low dose Maintenance chemotherapy | 50mg Etoposide (VP-16) 21 days on 7 off | No evidence of disease. |
| 6/07 | 0 | 0 | 0 | 0 |
| 7/07 | 0 | 0 | 0 | 0 |
| 8/07 | 0 | 0 | 0 | 0 |
| 9/23/07 | 0 | 0 | 0 | Diagnosed with Leukemia |
| 10/07 | 0 | Chemotherapy | 0 | 0 |
| 11/23/07 | 0 | 0 | 0 | Passed away. |
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