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In Memory

Smsunfl Nikki

Patient Information

Age: 12

Sex: Female

Diagnosed: 4/03

Location: Minnesota

Diagnosis: DSRCT

Hospital Children's Hospitals and Clinics of Minnesota

Oncologist

Relapse: 5/16/05 Tumor found between lungs.

Remission: No evidence of disease as of July 2006

Relapse: 9/23/07 diagnosed with Leukemia

Passed away: 11/23/07

Caringbridge Journal

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Treatment

First Line Chemotherapy

Cycle 1 - Adriamycin (Doxorubicin);Cytoxan (Cyclophosphamide); Vincristine
Cycle 2 - Etoposide, Ifosfamide, with Mesna
Gleevac given daily.

Radiation - 20+ sessions

Surgery #1 - Removed all visible tumors from pelvic area, underside of the liver, and top of the liver. Reports that 99% of the cancer cells were dead.

Chemotherapy

Etoposide and Ifosfamide
Gleevac given daily

Low Dose Maintenace Chemotherapy

1st Treatment: 100mg VP 16 (Etoposide) 21 days on and 7 off
2nd Treatment: 50mg VP 16 (Etoposide) 21 days on 7 off

Surgery #2 - Removed tumor that was a bit on the heart and in a nerve area.

Radiation - 4 -6 weeks after relapse

Chemotherapy - treatment for Leukemia

Time Line

Date Test Treatment Chemicals Result
4/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna Tumors in pelvic area, underside of the liver, and top of the liver.
5/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
5/18/03 0 0 0 Admitted to PICU with inflammation of brain
5/23/03 CT, MRI, spinal tap, EEG 0 0 Tumors shrinking considerably
6/15/03 0 Harvest stem cells 0 0
6/23/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
7/14/03 CT Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna Tumors continue to shrink
8/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
9/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
9/15/03 CT 0 0 Tumors still shrinking. One tumor has shrunk 3cm and is now 7cm. Watching three suspicious areas.
9/23/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
10/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
11/19/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
11/24/03 0 0 0 Fanconi Kidney caused by chemo. Has a leaky kidney. Needs to have phosphorus and magnesium, calcium and potassium levels monitored.
12/15/03 0 Chemotherapy Doxorubicin, Cytoxan, Vincristine, Etoposide, Ifosfamide, with Mesna 0
1/10/04 CT 0 0 Some tumors have gotten 1-2cm smaller. Area of concern is the liver area which showed 1 /2 inches by 2, which is larger than before. Few other suspicious mass areas, not conclusive for cancer.
1/22/04 0 Chemotherapy Etoposide and Ifosfamide 0
2/14/04 CT 0 0 Stable, set for surgery
2/18/04 0 Surgery 0 Removed all visible tumors from pelvic area, underside of the liver, and top of the liver. Reports that 99% of the cancer cells were dead.
3/04 0 Chemotherapy Etoposide and Ifosfamide, Gleevac 0
3/31/04 CT Radiation 20+ days 0 Noted a suspicious mass
4/14/04 PET 0 0 Mass was negative for cancer
5/3//04 0 Daily Gleevac 0 Finished radiation
5/26/04 CT 0 0 No change. Possible cysts around kidneys that have always been there.
6/04 0 Chemotherapy Etoposide and Ifosfamide 0
7/14/04 CT Chemotherapy Etoposide and Ifosfamide, Gleevac No visible signs, and even a small spot near liver has disappeared.
7/26/04 0 Chemotherapy Etoposide and Ifosfamide, Gleevac 0
8/04 0 0 Gleevac 0
9/3/04 0 Chemotherapy Etoposide and Ifosfamide, Gleevac 0
9/23/04 CT Low dose Maintenance chemotherapy Gleevac daily Clear. Still no tumors. Still see small area they believe are cysts.
10/04 0 0 Gleevac 0
11/5/04 CT 0 0 Still clear.
12/23/04 CT 0 0 Clear
1/25/05 CT 0 0 Clear, no evidence of disease.
2/05 0 Day surgery 0 Removed central line
3/14/05 CT 0 0 Clear
4/05 0 0 Gleevac 0
5/16/05 CT/PET 0 Gleevac Spot appeared between the lungs.
5/21/05 0 Biopsy 0 Relapse: Tumor between lungs
6/19/05 0 Surgery - four hours 0 Tumor was a bit on the heart and in a nerve area
7/25/05 CT 0 0 Baseline. Abdomen looks good. Still areas around lungs.
8/3/05 0 Radiation - next 4-6 weeks. Low dose Maintenance chemotherapy Stopped taking Gleevac. Started taking 100ml VP16/Etoposide daily. 0
8/15/05 PET Radiation. Low dose Maintenance chemotherapy 100mg Etoposide (VP-16) 21 days on 7 off Just area being radiated may or may not be tumor. Other spots are not tumor related.
9/05 0 0 0 Break from VP16/Etoposide
10/3/05 0 Low dose Maintenance chemotherapy 100mg Etoposide (VP-16) 21 days on 7 off 0
10/7/05 CT 0 0 Clear
11/05 0 0 0 Sample of tumor sent to Stehlin Foundation for Research
11/28/05 CT 0 0 Clear
12/05 0 0 0 0
1/24/06 CT 0 0 No evidence of disease
2/06 0 0 0 0
3/06 0 0 0 Off Etoposide
4/06 0 0 0 0
5/06 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
6/13/06 CT Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off No evidence of disease
7/28/06 CT Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off No evidence of disease
8/06 0 Low dose maintence chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
9/06 CT Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off No evidence of disease
10/06 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
11/06 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
12/06 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
1/15/07 CT Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off No evidence of disease.
2/07 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
3/07 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
4/07 0 Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off 0
5/15/07 CT Low dose Maintenance chemotherapy 50mg Etoposide (VP-16) 21 days on 7 off No evidence of disease.
6/07 0 0 0 0
7/07 0 0 0 0
8/07 0 0 0 0
9/23/07 0 0 0 Diagnosed with Leukemia
10/07 0 Chemotherapy 0 0
11/23/07 0 0 0 Passed away.


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