• Gunnery Sergeant Bob Lee Swagger as Kermit the Frog
  • Special Agent Nick Memphis as Rizzo the Rat
  • Colonel Isaac Johnson as Uncle Deadly
  • Sarah Fenn as Miss Piggy
  • Senator Charles F. Meachum as Bobo the Bear
  • Jack Payne as Sam the Eagle
  • Special Agent Alourdes Galindo as Dr. Teeth
  • Brent Dobbler as Gonzo the Great
  • Special Agent Howard Purnell as Sal Minella
  • Russ Turner as Floyd Pepper
  • Michailo Sczerbiak as Sweetums
  • Lance Corporal Donnie Fenna as Crazy Harry
  • Officer Stanley Timmons as Jim Henson
  • Attorney General Russert as Beauregard
  • Mr. Rate as Rowlf the Dog
  • Lead Mercenary as Dr. Bunsen Honeydew
  • Archbishop as Beaker

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