Smith
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[edit] In Memory
[edit] Patient Information
Age: 35
Sex: Female
Diagnosed: 11/95
Location: Olean, N.Y
Diagnosis: Grapefruit-sized tumor. Small number of isolated tumors that had not metastisized. DSRCT
Hospital
- Oncologist
Gynecological oncologist: Dr. David Marchetti, Buffalo, NY Consulted with Dr Brian Kushner
- Oncology (sarcoma) surgeon: Dr. Constantine Karacusus
- Millard Fillmore Hospital, Buffalo, NY
Passed Away: 08/06/01
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[edit] Treatment
Surgery
- Operated on for cyst. Found grapefruit-sized tumor and smaller isolated tumors that had not spred.
- Exploratory found no evidence of disease
Modified Intraperitoneal chemotherapy
- Infuse "normal" doses of the P-6 phase-two drugs (VP-16 and ifosfomide) through a peritoneal port in abdomen. Fluids would be absorbed back into the body, no draining. This procedure would be repeated three times.
Chemotherapy
- 1. Modified version of Kushner's P6 protocol (all at lower than recommended dosage)
- 3-day infusions of Cytoxan, Adriamycin and Vincristine (CAV).
- Three courses consisting of 5-day infusions of VP-16 and ifosfomide over 21-28 day cycles.
- 2. Modified version of P6 with DSMO
Alternative Medicine
- Therapeutic
- Astragalus, Coenzyme Q-10, Devil's Claw, Essiac Tea (2 oz.), Garlic, Maitaki, Red Clover, Shark Cartilage, Special Formula #1
- Cleansing
- Dandelion, Milk Thistle, Nettle
- Nutritional
- Acidophilus, Adrenal extract, Beta-Carotine, Calcium, Chamomile, Chromium, Ginger, Ginko Biloba, Ginsing, Multi-Vitamin, PABA, Pituitary extract, Spirulina, Thymus extract, Thyroid extract, Vitamin C, Digestive enzyme
- Pamela's Herbal & Nutritional Therapy Chart
- Chakra alignments
- Psychic healings
- Prayers and magic.
- Prayer Chains
[edit] Time Line
| Date | Test | Treatment | Chemicals | Result |
|---|---|---|---|---|
| 11/95 | 0 | 0 | 0 | 0 |
| 12/95 | 0 | 0 | 0 | 0 |
| 1/96 | 0 | 0 | 0 | 0 |
| 2/9/96 | 0 | Chemotherapy | Cytoxan, Adriamycin and Vincristine (CAV)- 3 day infusion | 0 |
| 3/96 | 0 | Chemotherapy | Cytoxan, Adriamycin and Vincristine (CAV) | 0 |
| 4/15/96 | CT | Chemotherapy | Cytoxan, Adriamycin and Vincristine (CAV) | Two fluid-like shadows near the cecum and the right kidney. A biopsy of the cecum appeared to be scar-tissue of tumor origin. The other small tumors seen during the laparoscopy in January had disappeared completely. |
| 4/96 | 0 | Surgery | 0 | Removed the two masses. The cecum proved to be all scar tissue while the tumor near the kidney had a small number of active cells deep within the mass. |
| 5/96 | 0 | Chemotherapy | Cytoxan, Adriamycin and Vincristine (CAV) | 0 |
| 6/13/96 | CT | 0 | 0 | Clear. No evidence of disease. |
| 7/8/96 | 0 | Chemotherapy -5 days | VP-16 and ifosfomide | 0 |
| 8/96 | 0 | Chemotherapy -5 days | VP-16 and ifosfomide | 0 |
| 9/96 | 0 | Chemotherapy -5 days | VP-16 and ifosfomide | 0 |
| 10/96 | PET | 0 | 0 | No evidence of disease or metastatic progression |
| 11/2/96 | 0 | Exploratory surgery and wash | 0 | No evidence of disease |
| 11/8/96 | 0 | Intraperitoneal chemotherapy 1 | VP-16 and ifosfomide | 0 |
| 12/6/96 | 0 | Intraperitoneal chemotherapy 2 | VP-16 and ifosfomide | 0 |
| 1/27/97 | 0 | Intraperitoneal chemotherapy 3 | VP-16 and ifosfomide | 0 |
| 2/20/97 | 0 | Intraperitoneal chemotherapy 4 | DMSO dissolved in VP-16. Ifosfomide was administered IV. | 0 |
| 3/97 | 0 | Intraperitoneal chemotherapy 5 | DMSO dissolved in VP-16. Ifosfomide was administered IV. | 0 |
| 4/97 | 0 | Intraperitoneal chemotherapy 6 | DMSO dissolved in VP-16. Ifosfomide was administered IV. | 0 |
| 5/97 | 0 | Intraperitoneal chemotherapy 6 | DMSO dissolved in VP-16. Ifosfomide was administered IV. | 0 |
| 6/97 | CT | 0 | 0 | No evidence of disease |
| 7/97 | 0 | 0 | 0 | 0 |
| 8/97 | 0 | 0 | 0 | 0 |
| 8/97 | 0 | 0 | 0 | 0 |
| 9/97 | CT | 0 | 0 | No evidence of disease |
| 10/97 | 0 | 0 | 0 | 0 |
| 11/28/97 | PET | 0 | 0 | No evidence of disease |
| 12/97 | 0 | 0 | 0 | 0 |
| 1/98 | 0 | 0 | 0 | 0 |
| 2/98 | 0 | 0 | 0 | 0 |
| 3/98 | 0 | 0 | 0 | 0 |
| 4/98 | CT | 0 | 0 | Cyst on ovary, will check in July |
| 5/98 | 0 | 0 | 0 | 0 |
| 6/98 | 0 | 0 | 0 | 0 |
| 7/17/98 | CT | Surgery- removed ovary, had a hysterectomy | 0 | Cyst on ovary. |
| 8/98 | 0 | 0 | 0 | 0 |
| 9/98 | 0 | 0 | 0 | 0 |
| 10/98 | 0 | 0 | 0 | 0 |
| 11/98 | CT | 0 | 0 | No evidence of disease |
| 12/98 | 0 | 0 | 0 | 0 |
| 1/99 | 0 | 0 | 0 | 0 |
| 2/99 | 0 | 0 | 0 | 0 |
| 3/99 | 0 | 0 | 0 | 0 |
| 4/99 | CT | 0 | 0 | No evidence of disease |
| 5/99 | 0 | 0 | 0 | 0 |
| 6/99 | 0 | 0 | 0 | 0 |
| 7/99 | 0 | 0 | 0 | 0 |
| 8/99 | 0 | 0 | 0 | 0 |
| 9/99 | 0 | 0 | 0 | 0 |
| 10/99 | 0 | 0 | 0 | 0 |
| 11/24/99 | CT | 0 | 0 | No evidence of disease |
| 12/99 | 0 | 0 | 0 | 0 |
| 1/00 | 0 | 0 | 0 | 0 |
| 2/00 | 0 | 0 | 0 | 0 |
| 3/00 | 0 | 0 | 0 | 0 |
| 4/22/00 | 0 | 0 | 0 | CT delayed, rescheduled |
| 5/00 | 0 | 0 | 0 | 0 |
| 6/29/00 | Full body CT scan | 0 | 0 | Questionable image near the start of the small bowel. |
| 7/25/00 | MRI | 0 | 0 | 4cm by 6cm mass was visualized near the Porta Hepata of the liver. |
| 8/7/00 | 0 | Surgery | 0 | After 8 hours unable to resect the entire tumor. It had entwined itself within the venous area of the Porta Hepata and approximately 70% of it was impossible to remove. |
| 8/24/00 | 0 | Chemotherapy 1 - Modified version of P6 | Cytoxan dissolved in a 10% solution of DMSO along with the 3-day infusion of Vincristine. Adriamycin is being left out. | 0 |
| 9/00 | 0 | Chemotherapy 2 - Modified version of P6 | Cytoxan dissolved in a 10% solution of DMSO & Vincristine | 0 |
| 10/00 | 0 | Chemotherapy 3 - Modified version of P6 | Cytoxan dissolved in a 10% solution of DMSO & Vincristine | 0 |
| 11/15/00 | CT | 0 | 0 | No change in size of tumor |
| 12/00 | 0 | 0 | 0 | 0 |
| 1/01 | 0 | Chemotherapy | Taxol/Cisplatin | 0 |
| 2/01 | 0 | Chemotherapy | Taxol/Cisplatin | 0 |
| 3/01 | 0 | Chemotherapy | Taxol/Cisplatin | No change in tumor |
| 4/01 | 0 | Chemotherapy | Hexalene, an oral drug | 0 |
| 5/01 | 0 | Chemotherapy | Hexalene, an oral drug | Stopped taking, too harsh |
| 6/01 | 0 | 0 | 0 | First time needing blood transfusions - does not go well. Poor liver function. |
| 7/11/01 | 0 | 0 | 0 | Stopped all treatment. On hospice care. |
| 8/6/01 | 0 | 0 | 0 | Passed Away |
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