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In Memory

Smsunfl Pamela

Patient Information

Age: 35

Sex: Female

Diagnosed: 11/95

Location: Olean, N.Y

Diagnosis: Grapefruit-sized tumor. Small number of isolated tumors that had not metastisized. DSRCT

Hospital

Oncologist

Gynecological oncologist: Dr. David Marchetti, Buffalo, NY Consulted with Dr Brian Kushner

Oncology (sarcoma) surgeon: Dr. Constantine Karacusus
Millard Fillmore Hospital, Buffalo, NY

Passed Away: 08/06/01

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Treatment

Surgery

Operated on for cyst. Found grapefruit-sized tumor and smaller isolated tumors that had not spred.
Exploratory found no evidence of disease

Modified Intraperitoneal chemotherapy

Infuse "normal" doses of the P-6 phase-two drugs (VP-16 and ifosfomide) through a peritoneal port in abdomen. Fluids would be absorbed back into the body, no draining. This procedure would be repeated three times.


Chemotherapy

1. Modified version of Kushner's P6 protocol (all at lower than recommended dosage)
3-day infusions of Cytoxan, Adriamycin and Vincristine (CAV).
Three courses consisting of 5-day infusions of VP-16 and ifosfomide over 21-28 day cycles.
2. Modified version of P6 with DSMO

Alternative Medicine

Therapeutic
Astragalus, Coenzyme Q-10, Devil's Claw, Essiac Tea (2 oz.), Garlic, Maitaki, Red Clover, Shark Cartilage, Special Formula #1
Cleansing
Dandelion, Milk Thistle, Nettle
Nutritional
Acidophilus, Adrenal extract, Beta-Carotine, Calcium, Chamomile, Chromium, Ginger, Ginko Biloba, Ginsing, Multi-Vitamin, PABA, Pituitary extract, Spirulina, Thymus extract, Thyroid extract, Vitamin C, Digestive enzyme
Pamela's Herbal & Nutritional Therapy Chart
Chakra alignments
Psychic healings
Prayers and magic.
Prayer Chains

Time Line

Date Test Treatment Chemicals Result
11/95 0 0 0 0
12/95 0 0 0 0
1/96 0 0 0 0
2/9/96 0 Chemotherapy Cytoxan, Adriamycin and Vincristine (CAV)- 3 day infusion 0
3/96 0 Chemotherapy Cytoxan, Adriamycin and Vincristine (CAV) 0
4/15/96 CT Chemotherapy Cytoxan, Adriamycin and Vincristine (CAV) Two fluid-like shadows near the cecum and the right kidney. A biopsy of the cecum appeared to be scar-tissue of tumor origin. The other small tumors seen during the laparoscopy in January had disappeared completely.
4/96 0 Surgery 0 Removed the two masses. The cecum proved to be all scar tissue while the tumor near the kidney had a small number of active cells deep within the mass.
5/96 0 Chemotherapy Cytoxan, Adriamycin and Vincristine (CAV) 0
6/13/96 CT 0 0 Clear. No evidence of disease.
7/8/96 0 Chemotherapy -5 days VP-16 and ifosfomide 0
8/96 0 Chemotherapy -5 days VP-16 and ifosfomide 0
9/96 0 Chemotherapy -5 days VP-16 and ifosfomide 0
10/96 PET 0 0 No evidence of disease or metastatic progression
11/2/96 0 Exploratory surgery and wash 0 No evidence of disease
11/8/96 0 Intraperitoneal chemotherapy 1 VP-16 and ifosfomide 0
12/6/96 0 Intraperitoneal chemotherapy 2 VP-16 and ifosfomide 0
1/27/97 0 Intraperitoneal chemotherapy 3 VP-16 and ifosfomide 0
2/20/97 0 Intraperitoneal chemotherapy 4 DMSO dissolved in VP-16. Ifosfomide was administered IV. 0
3/97 0 Intraperitoneal chemotherapy 5 DMSO dissolved in VP-16. Ifosfomide was administered IV. 0
4/97 0 Intraperitoneal chemotherapy 6 DMSO dissolved in VP-16. Ifosfomide was administered IV. 0
5/97 0 Intraperitoneal chemotherapy 6 DMSO dissolved in VP-16. Ifosfomide was administered IV. 0
6/97 CT 0 0 No evidence of disease
7/97 0 0 0 0
8/97 0 0 0 0
8/97 0 0 0 0
9/97 CT 0 0 No evidence of disease
10/97 0 0 0 0
11/28/97 PET 0 0 No evidence of disease
12/97 0 0 0 0
1/98 0 0 0 0
2/98 0 0 0 0
3/98 0 0 0 0
4/98 CT 0 0 Cyst on ovary, will check in July
5/98 0 0 0 0
6/98 0 0 0 0
7/17/98 CT Surgery- removed ovary, had a hysterectomy 0 Cyst on ovary.
8/98 0 0 0 0
9/98 0 0 0 0
10/98 0 0 0 0
11/98 CT 0 0 No evidence of disease
12/98 0 0 0 0
1/99 0 0 0 0
2/99 0 0 0 0
3/99 0 0 0 0
4/99 CT 0 0 No evidence of disease
5/99 0 0 0 0
6/99 0 0 0 0
7/99 0 0 0 0
8/99 0 0 0 0
9/99 0 0 0 0
10/99 0 0 0 0
11/24/99 CT 0 0 No evidence of disease
12/99 0 0 0 0
1/00 0 0 0 0
2/00 0 0 0 0
3/00 0 0 0 0
4/22/00 0 0 0 CT delayed, rescheduled
5/00 0 0 0 0
6/29/00 Full body CT scan 0 0 Questionable image near the start of the small bowel.
7/25/00 MRI 0 0 4cm by 6cm mass was visualized near the Porta Hepata of the liver.
8/7/00 0 Surgery 0 After 8 hours unable to resect the entire tumor. It had entwined itself within the venous area of the Porta Hepata and approximately 70% of it was impossible to remove.
8/24/00 0 Chemotherapy 1 - Modified version of P6 Cytoxan dissolved in a 10% solution of DMSO along with the 3-day infusion of Vincristine. Adriamycin is being left out. 0
9/00 0 Chemotherapy 2 - Modified version of P6 Cytoxan dissolved in a 10% solution of DMSO & Vincristine 0
10/00 0 Chemotherapy 3 - Modified version of P6 Cytoxan dissolved in a 10% solution of DMSO & Vincristine 0
11/15/00 CT 0 0 No change in size of tumor
12/00 0 0 0 0
1/01 0 Chemotherapy Taxol/Cisplatin 0
2/01 0 Chemotherapy Taxol/Cisplatin 0
3/01 0 Chemotherapy Taxol/Cisplatin No change in tumor
4/01 0 Chemotherapy Hexalene, an oral drug 0
5/01 0 Chemotherapy Hexalene, an oral drug Stopped taking, too harsh
6/01 0 0 0 First time needing blood transfusions - does not go well. Poor liver function.
7/11/01 0 0 0 Stopped all treatment. On hospice care.
8/6/01 0 0 0 Passed Away

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