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- Brainy Smurf as Shrek
- Dreamy Smurf as Donkey
- Smurfette as Princess Fiona
- Vanity Smurf as Puss In Boots
- Hefty Smurf as King Harold
- Sassette Smurfling as The Dragon
- Gargamel as Lord Farquaad
- Weepy Smurf as Gingy