- Soleil Spacebot (The Spacebots) as Kim Possible
- Sam Spacebot (The Spacebots) as Ron Stoppable
- Jerry (Tom and Jerry) as Rufus
- Dizzy (Rock & Rule) as Wade Load
- Tulio (Rio and Rio 2) as Dr. James Possible
- Linda (Rio and Rio 2) as Ann Possible
- Lucas Nickle (The Ant Bully) and Yankee Irving (Everyone's Hero) as Kim's Brothers
- Commander Zurg (The Spacebots) as Dr. Drakken
- Martian Queen (Duck Dodgers) as Shego
- Shreeky (The Care Bears Family) as Bonnie
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