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- Sonic as Homer Simpson
- Sally Acorn as Marge Simpson
- Kirby (from Kirby) as Bart Simpson
- Tiff (from Kirby) as Laura Powers
- Cream as Lisa Simpson
- Tokkori (from Kirby) as Milhouse Von Houten
- Tails as Lenny Leopard
- Amy Rose as Maude Flanders
- Knuckles as Nelson
- King Dedede (from Kirby) as Principal Skinner