- Stan Marsh as Lighting McQueen (Stan and Lighting McQueen are both the main stars of the series)
- Kyle Broflovski as Mater
- Wendy Testaburger as Sally
- Eric Cartman as Red
- Butters Stotch as Fillmore
- Mr. Garrison as Doctor Hudson
- Randy Marsh as Sheriff
- Scott Tenorman as Chick Hicks
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