- Lisa Simpson as Ginormica
- Moe the Bartender as Missing Link
- Comic Book Guy as BOB the Blob
- Proffesor Frink as Dr. Cockroach
- Maggie as Insectasaurus
- Cheif Wiggum as General Monger
- Mayor Quimby as the President
- The Rigelians as Galaxarrrs Clones
- Milhouse as Derek
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