- Babydoll as Misty
- Sweet Pea as Dawn
- Rocket as May
- Madame Vera Gorski / Dr. Vera Gorski as Nurse Joy
- Blue Jones as Ash Ketchum
- The Doctor / The High Roller as Professor Oak
- The Wise Man / The General / The Bus Driver as Pikachu
- The Stepfather as Max
- Earl as Gary Oak
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