- Catherine Holly as Miss Piggy
- Mrs. Violet Venable as Annie Sue Pig
- Dr. John Cukrowicz as Kermit the Frog
- Dr. Lawrence Hockstader as Robin the Froz
- Grace as Camilla the Chicken
- George as Gonzo the Great
- Miss Foxhill as Janice
- Nurse Benson as Wanda
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