Cast[]
- The Simpsons Characters as Thomas and His Friends
- Lenny as Sunshine
- Grandpa Abe as Toby
- Helen Lovejoy as Mavis
- Mayor Quimby as Sir Topham Hatt
- South Park Characters as TUGS Characters
- Stan Marsh as Ten Cents
- Chef as Big Mac
- Mr. Garrison as OJ
- Randy Marsh as Top Hat
- Gerald Broflovski as Warrior
- Stuart McCormick as Hercules
- Kenny McCormick as Sunshine
- Mr. Mackey as Captain Star
- Eric Cartman as Zorran
- Phillip as Zug
- Terrence as Zip
- Satan as Captain Zero
- Wendy Testaburger as Lillie Lightship
- Sharon Marsh as Sally Seaplane
- Hercules as Postman Pat
- Ten Cents as Fireman Sam
- Carla (from TT) as Angelica Pickles
- Warrior, Sigrid (from TT), Top Hat and Sally Seaplane as Homer, Marge, Bart and Lisa
- Lillie Lightship as Noddy
- Izzy Gomez as Bert Monkey
- Sunshine as Bumpy Dog
- Emily (from TT) as Tessie Bear
- Pugwash (from TT) as Dinah Doll
- Billy Shoepack as Clockwork Mouse
- Bluenose as Master Tubby Bear