- Fireman Sam as Indiana Jones
- Big Ears as Henry Jones Sr.
- Stan Marsh as Mutt Williams
- Noddy as Marion Ravenwood
- Lisa Simpson as Elsa Schneider
- Wendy Testaburger as Willie Scott
- Kenny McCormick as Short Round
- Mr. Plod as Sallah
- Angelica Pickles as Irina Spalko
- Gobbo as Rene Belloq
- Eric Cartman as Walter Donovan
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