- Ociee Nash as Marge Simpson
- Woofer as Homer Simpson
- Gypsy John Leon as Bart Simpson
- Ben Nash as Moe Syzlak
- Papa George Nash as Mayor Joe Quimby
- Fred Nash as Waylon Smithers, Jr.
- Miss June as Lisa Simpson
- Conductor Mr. Charles as Principal Seymour Skinner
- Nelly Bly as Maude Flanders
- Conductor Mr. Louis as Grandpa Abe Simpson
- President William McKinley as Chief Clancy Wiggum
- Wilbur Wright as Lenny
- Orville Wright as Carl
- Mr. Lynch as Kent Brockman
- Aunt Mamie Nash as Patty Bouvier
- Elizabeth Murphy as Selma Bouvier
- Frances Murphy as Maggie Simpson
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