- Lucy Warriner as Misty
- Jerry Warriner as Ash Ketchum
- Dan Leeson as Pikachu
- Armand Duvalle as Brock
- Aunt Patsy as Dawn
- Barbara Vance as May
- Mrs. Leeson as Zoey
- Dixie Belle Lee as Nurse Joy
- Frank Randall as Cilan
- Mr. Vance as Buizel
- Mrs. Vance as Francesca Ketchum
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