- Lucy Muir as Lois Griffin
- Daniel Gregg as Peter Griffin
- Miles Fairley as Chris Griffin
- Martha Huggins as Dr. Amanda Rebecca
- Anna Muir as Meg Griffin
- Mrs. Fairley as Jillian
- Mr. Coombs as Bruce
- Eva as Connie D'Amico
- Man Ordered Out of Train Compartment by Captain as Mayor Adam West
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