- Arlo as Paddington
- Poppa as Mr. Brown
- Spot as Jonathan Brown
- Ivy as Judy Brown
- Claire Wheeler (from Monsters University) as Mrs. Bird
- Johnny (from Monsters University) as Mr. Gruber
- Forrest as Mr. Curry
- Brock Pearson (from Monsters University) as Uncle Pastuzo
- Momma as Aunt Lucy
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