• Irwin as Jimmy Neutron
  • Stan Marsh (From South Park) as Carl Wheezer
  • Billy as Sheen Estevez (both are dumb)
  • Mindy as Cindy Vortex
  • Mandy as Libby
  • Gladys as Judy Neutron
  • Harold as Hugh Neutron
  • Grim as King Goobat V
  • The Wasp#1 (From Maya the Bee) as Ooblar

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