- Dr. Alec Considine as Kermit the Frog
- Dr. John Paul Otis as Rizzo the Rat
- Lisa Cardigan as Miss Piggy
- Dr. Lew Worship as Gonzo the Great
- Gloria as Annie Sue Pig
- Dr. Sid Lackland as Floyd Pepper
- Dr. Sidney Wohl as Walter
- Dr. Dominic Riccio as Beauregard
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