• Elroy Jetson as Mario
  • Astro the Dog as Luigi
  • George Jetson as Wario
  • Mr. Cogswell as Waluigi
  • Orbitty as Yoshi
  • Judy Jetson as Peach
  • Jane Jetson as Daisy
  • Rosie the Robot Maid as Rosalina
  • Mrs. Spacely as Toadette
  • Arthur Spacely as Toad
  • Mugsy Megatron as Donkey Kong
  • Knuckles Nuclear as Diddy Kong
  • Mr. Spacely as Bowser
  • The Gripfather as Bowser Jr.

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