• Elroy Jetson as Mario
  • Astro the Dog as Luigi
  • Judy Jetson as Peach
  • Orbitty as Yoshi
  • George Jetson as Wario
  • Jane Jetson as Daisy
  • Mr. Cogswell as Waluigi
  • Arthur Spacely as Toad
  • Zero the Dog as Boo
  • The Gripfather as Koopa Kid
  • Miss Galaxy as Toadette
  • Henry Orbit as Donkey Kong
  • Mr. Spacely as Bowser
  • Kenny as Red Koopa Kid
  • Irvin as Green Koopa Kid
  • Jimmy as Blue Koopa Kid
  • Rosie the Robot Maid as Twila
  • Mac the Robot Man as Brighton

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