• Elroy Jetson as Mario
  • Astro the Dog as Luigi
  • Judy Jetson as Peach
  • Orbitty as Yoshi
  • George Jetson as Wario
  • Jane Jetson as Daisy
  • Mr. Cogswell as Waluigi
  • Arthur Spacely as Toad
  • Zero the Dog as Boo
  • Miss Galaxy as Toadette
  • Rosie the Robot Maid as Birdo
  • Mac the Robot Man as Dry Bones
  • Kenny as Blooper
  • Irvin as Hammer Bro.
  • Knuckles Nuclear as MC Ballyhoo
  • Mugsy Megatron as Big Top
  • Henry Orbit as Donkey Kong
  • Mr. Spacely as Bowser

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