• Elroy Jetson as Phil Diffy
  • Judy Jetson as Pim Diffy
  • George Jetson as Lloyd Diffy
  • Jane Jetson as Barb Diffy
  • Rosie the Robot Maid as Keeley Teslow
  • Mr. Spacely as Vice Principal Neil Hackett
  • Henry Orbit as Curtis the Caveman
  • Mrs. Meltdown as Ms. Winston
  • Miss Galaxy as Debbie Berwick
  • Kenny Countdown as Bradley Farmer
  • Astro the Dog as Seth Wosmer
  • George's Mother as Neckbrace Lana
  • Mr. Cogswell as Tanner Kirkpatrick
  • Jane's Mom as Tia
  • Melissa as Candida
  • Ralph as Lil Danny Dawkins
  • R.U.D.I as Joel Messerschmit
  • Emily Scopes as Olivia
  • Orbitty as Owen

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