• Elroy Jetson as Moe Howard
  • Orbitty as Larry Fine
  • Astro the Dog as Curly Howard
  • George Jetson as Shemp Howard
  • Henry Orbit as Joe Besser
  • Arthur Spacely as Curly Joe DeRita
  • Judy Jetson as Moe's Girlfriend
  • Miss Galaxy as Larry's Girlfriend
  • Rosie the Robot Maid as Curly's Girlfriend, Shemp's Girlfriend, Joe's Girlfriend, and Curly Joe's Girlfriend
  • Zero as Puppy
  • Mr. Spacely as Mac
  • Mrs. Spacely as Lydia
  • Mr. Cogswell as Mr. Harter
  • R.U.D.I as Teddy O Hara
  • History as Nippy
  • The Gripfather as Sister Mary-Mengele
  • Mrs. Galaxy as Sister Rosemary
  • Skata-Hara as Sister Bernice
  • Jane's Mother as Sister Ricarda
  • Mr. Transitor as Monsignor

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