- Alex Wyler as Kermit the Frog
- Kate Forster as Miss Piggy
- Simon J. Wyler as Rizzo the Rat
- Henry Wyler as Dr. Teeth
- Dr. Anna Klyczynski as Gonzo the Great
- Morgan Price as Dr. Bunsen Honeydew
- Mrs. Forster as Camilla the Chicken
- Mona as Annie Sue Pig
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