- Emma Wilder as Marge Simpson
- Noah Wilder as Homer Simpson
- David Wilder as Bart Simpson
- Jo Wilder as Lisa Simpson
- Larry White as Ralph Wiggum
- Naomi Schwartz as Patty Bouvier
- FBI Special Agent Nathaniel Broadman as Grandpa Abe Simpson
- FBI Task Force Agent as Snake Jailbird
- Sheila Broadman as Edna Krabappel
- Harry Jones as Mr. Burns
- Wendy as Bernice Hibbert
- Lena as Maggie Simpson
- Brian Greene as Chief Clancy Wiggum (cameo)
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