- Leo Lionheart Jr. as Peter Griffin
- Lana Lionheart as Meg Griffin
- Kate Lionheart as Lois Griffin
- Spencer Lionheart as Chris Griffin
- Judy Lionheart as Dr. Amanda Rebecca
- Grandpa Leo as Mayor Adam West
- Director as Cleveland Brown
- Dorothy as Jillian
- Freddy as Dr. Hartman
- Jennings as Glenn Quagmire
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