• Sam Spade as Ash Ketchum
  • Brigid O'Shaughnessy as Misty
  • Iva Archer as Nurse Joy
  • Joel Cairo as Pikachu
  • Lt. of Detectives Dundy as Professor Birch
  • Effie Perrine as May
  • Kasper Gutman as Brock
  • Detective Tom Polhaus as Ritchie
  • Miles Archer as Max
  • Wilmer Cook as Gary Oak
  • Luke as Mewtwo
  • Bryan as Meowth

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