The New Adventures of George Jetson is a 'TV/New Adventures of Winnie the Pooh' parody.
George Jetson (The Jetsons) as Winnie the Pooh - George Jetson, or George, for short, is an anthropomorphic astronaut. Despite being "an astronaut of very little brain", he is a friendly and thoughtful character. His love for adventure sometimes leads to trouble. His catchphrases are "Oh, bother!" and "Think, George, Think". He is voiced by Jeff Bergman.
Mr Nervous (The Mr Men Show) as Piglet - Mr Nervous, George's best friend, is a kind, tidy purple Mr Men who is ordinarily quite timid, but with George by his side, he often overcomes his fears. He lives in a log cabin, sings very well and likes to eat peanut butter. He is voiced by Danny Katiana.
Marty (Madagascar) as Tigger - Marty is George's brave, exuberant and trouble-making zebra pet. He loves to go crazy and have fun, but sometimes bumps into others. He is voiced by Chris Rock.
Wally Llama (Animaniacs) as Rabbit - Wally Llama is George, Mr Nervous and Marty's bossy, but mostly kind friend who takes care of the characters until they go to sleep. He likes thinking that he is the smartest person in Toontown, but can get very angry when Marty ruins his prized garden. He is voiced by Richard Libertini.
Mr Lazy (The Mr Men Show) as Eeyore - Mr Lazy is George's ever-glum, fast-talking, pessimistic Mr Men friend. He has trouble completing his adventure sculpture because it is always being destroyed (mainly destroyed by Marty). He is voiced by Phil Lollar.
Strong Bad (Homestar Runner) as Gopher
Marge (The Simpsons Movie) as Kanga
Bart (The Simpsons Movie) as Roo
Mr Persnickety (The Mr Men Show) as Owl
Andy Davis (Toy Story) as Christopher Robin
Duncan (Thomas the Tank Engine) as Bruno the Wind Up Monkey
Dot (Animaniacs) as Kessie
Barkerville (Pound Puppies) as Papa Heffalump
Jenna (Balto) as Mama Heffalump
Wilson (Good Boy) as Junior Heffalump
Little Miss Naughty (The Mr Men Show) as Babysitter
Frankie (Foster's Home for Imaginary Friends) as Andy's Mom
Dingers (Sesame Street) as Crows
Mason (Madagascar) as Dexter
Aliens (Toy Story) as Pack Rats
Senor Cardgage (Homestar Runner) as Gopher's Grandfather
Horrid Lorries (Thomas the Tank Engine) as Bees
Pal (Arthur) as Skippy
Mr Grumpy (The Mr Men Show) as Wooster
Plankton (Spongebob Squarepants) as Stan the Woozle
Tramp (Lady and the Tramp) as Heff the Heffalump
Mr Rude (The Mr Men Show) as Crud
Norman Price (Fireman Sam) as Smudge
Sea Rogue (TUGS) as Nasty Jack