- Reverend Frank Scott as Peter Griffin
- Detective Lieutenant Mike Rogo as Chris Griffin
- Linda Rogo as Lois Griffin
- James Martin as Dr. Hartman
- Nonnie Parry as Dr. Amanda Rebecca
- Belle Rosen as Meg Griffin
- Manny Rosen as Glenn Quagmire
- Acres as Cleveland Brown
- Susan Shelby as Susie Swanson
- Chaplain John as Jesus
- Captain Harrison as Mayor Adam West
- First Officer Larsen as Joe Swanson
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