- Max as Alvin
- Reginald as Simon
- E.B. (from Hop) as Theodore
- Gidget as Brittany
- Chloe as Jeanette
- Fluffy (from Hop) as Eleanor
- Gru (from Despicable Me 2) as Dave Seville
- Lucy (from Despicable Me 2) as Samantha
- Vector (from Despicable Me) as Miles
- Mr. Perkins (from Despicable Me) as Agent James Suggs
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